Thank you all for your responses. My issue has been resolved. I run Windows 7, and have a Programe Files Folder and Programe Files (x86) Folder in my Directory. Both Program File Folders have Sony and Everquest2 Folders and neither EverQuest2.exe worked, hence nor did my ProfitUI and EQ2Map Updater.
I do however, have the streamer EverQuestII icon on my desktop that does work, but still without ProfitUI. I checked the pathing, and low and behold a Folder named ProgramData appears, but didn't show in my Directory. So, after using the Control Panel to show hidden files and folders , I was then able to follow the pathing and point my ProfitUI to that EverQuest2.exe, which was the working one, and now all works perfectly.
Can't help with the 5k plat, but I feel as though I've won a million.
Thank you again for all your help