Most windows in the UI have a blue "gem" button in the upper left-hand corner when you mouse over the area. Click that and you'll get the window manager where you can change settings. For the window you mentioned, uncheck the box for "Listen to Maintained spells" and then click Save. The Spell Monitor should stay hidden from that point forward.
If all buffs are not visible, the Maintained Spells window may be too small to show everything. Press F10 to show all windows, and resize Maintained Spells larger if needed. Press F10 twice more to go back to normal view.
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