Aye, I run normal textures on medium or high. The terrain textures really aren't usually all that extravagant, especially if it's just dirt/whatever.
Character textures however have a definite difference when you go from high to maximum. You can really see all the little tiny crevices and details of the armor and the weapons and such. I don't normally play with maximum, especially if I'm raiding. I like to keep it high, but I hate switching back and forth all the time. So, I usually just find a "medium" between the two.
Now I think I'll be able to play in a higher setting all of the time