I currently use the Profit UI along with EQ2 Map and Map Spoiler addon, however the spoiler window doesn't toggle with the map like it should, and does if I don't use profit UI.
Experience is an EQ2 problem and it is a known issue.
EQ2 Map Spoiler is an add on that is not part of the ProfitUI. On the boards for this addon, the author has been notified about this issue and he is trying to find a way to make it work.