Before you go and try custom UIs, have you tried using the various font options in-game first? I know under the options somwhere, I believe it's listed under UI, there are a couple choices to change the in-game font to a "smooth" version, and to change to a different font type all-together.
You may want to check those out before you try a custom UI, I know those optional in-game fonts were made specifically for people that were having problems seeing and/or reading the default fonts so it may very well be exactly what you're looking for.
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