from what i have read and have come to understand is that people who have purchased a copy of EQ2 in a diff language and installed another diff language (i.e. bought german copy, installed as english) that directory is made.
Inside that directory is pretty much ANOTHER copy of all the files for eq2, resulting in twice the space taken on your HD, which is a hefty 8gigs or so.
I believe that LP_REGION_EN_US has all the files that are used and the other files are obsolete....
Hope this helps...
Tony
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I_love